Preliminary Programme
Monday 12 December |
12.00 - 14.00
Registration
Foyer, Rootes Social Building
12.00 - 13.30
Lunch
14.00 - 14.05
Opening Remarks
Richard Marais (London)
Session 1: Chromosome biology and cell proliferation
Chair: Jordan Raff
14.05 - 14.35
Monica Bettencourt-Dias (Oeiras)
"Centrosome biogenesis: Right number, right time and only once"
14.35 - 15.05
Ivan Ahel (Manchester)
"Poly(ADP-ribosyl)ation in regulation of DNA repair"
15.05 - 15.35
Andrew McAinsh (Warwick)
"Chromosome Navigation: finding the way to the middle ground"
Tea/Coffee Break
Chair: Karim Labib
16.05 - 16.35
Mark Petronczki (London)
"Cell Division and Aneuploidy"
16.35 - 17.05
Asifa Akhtar (Freiburg)
"Dosage compensation in Drosophila"
17.05 - 17.35
Dan Durocher (Toronto)
"Ubiquitin as an organizer of the DNA damage response"
Dinner
20.00 - 21.00
Keynote Lecture (Chaired by Richard Marais)
Adrian Bird (Edinburgh)
"CpG as a genomic signalling module"
Tuesday 13 December |
Session 2: The role of ubiquitin and sumo in cancer
Chair: Pascal Meier
09.00 - 09.30
Wade Harper (Boston)
"Proteomic Exploration of the Ubiquitin-Protreasome System"
09.30 - 10.00
Sylvie Urbé (Liverpool)
"Control of Cellular Dynamics by Reversible Ubiquitination"
10.00 - 10.30
Ron Hay (Dundee)
"Role of the SUMO-targetted ubiquitin ligase Rnf4 in the DNA damage response"
Tea/Coffee Break
Chair: Sonia Rocha
11.00 - 11.30
Henning Walczak (London)
"Linear ubiquitination as a regulator of cell death and inflammation"
11.30 - 12.00
Philip Cohen (Dundee)
Regulation of protein kinases controlling innate immunity - potential links to cancer?
12.00 - 12.30
Two short talks selected from submitted abstracts
Lunch with Posters and Trade Exhibition
Session 3: Frontiers in cancer research
Chair: Kevin Ryan
14.30 - 16.30
Keith Flaherty (Boston)
"BRAF inhibition in the clinic reveals liabilities and opportunities"
15.00 - 15.30
Laura Johnston (New York)
"Homeostatic cell-cell interactions during growth"
15.30 - 16.00
Steve Jackson (Cambridge)
"Cellular responses to DNA damage"
Posters and Trade Exhibition
Conference Dinner
Ceilidh and late bar
Wednesday 14 December |
Session 4: The use of mouse models to investigate cancer processes
Chair: John Rouse
09.30 - 10.00
Jos Jonkers (Amsterdam)
"Therapy response and resistance in conditional mouse models of breast cancer"
10.00 - 10.30
Leisa Johnson (San Francisco)
"Genetic and preclinical interrogation of genetically engineered mouse models of lung cancer"
Tea/Coffee Break
11.00 - 11.30
Erik Sahai (London)
"Imaging the metastatic process"
11.30 - 12.00
John Silke (Melbourne)
"The role of IAPs in regulating inflammation and tumour development"
12.00 - 12.30
Paul Martin (Bristol)
"Parallels between wound healing and cancer"
12.30 - 12.35
Closing Remarks
Richard Marais (London)
Lunch
